Biomaterial Database

[Changes in the enzyme-active region of the neuromuscular synapse of the gastrocnemius muscle in rats during hypokinesis]. 1996

V V Shilkin, and V I Filimonov, and P P Potapov

Restraint of white rats in fight cages leads to diminution of the area of neuromuscular synapse with an intricate structure of the enzyme-active region and reduction of the number of neuromuscular synapses per one fiber in the gastrocnemius muscle. Signs of dystrophy of neuromuscular synapses with the intricate enzyme-active region are observed. These changes arise by day 14 of hypokinesia and become more pronounced by day 28.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009469	Neuromuscular Junction	The synapse between a neuron and a muscle.	Myoneural Junction,Nerve-Muscle Preparation,Junction, Myoneural,Junction, Neuromuscular,Junctions, Myoneural,Junctions, Neuromuscular,Myoneural Junctions,Nerve Muscle Preparation,Nerve-Muscle Preparations,Neuromuscular Junctions,Preparation, Nerve-Muscle,Preparations, Nerve-Muscle
D002802	Cholinesterases		Acylcholineacylhydrolase,Cholase,Cholinesterase
D006651	Histocytochemistry	Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.	Cytochemistry
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D018476	Hypokinesia	Slow or diminished movement of body musculature. It may be associated with BASAL GANGLIA DISEASES; MENTAL DISORDERS; prolonged inactivity due to illness; and other conditions.	Bradykinesia,Hypodynamia,Hypokinesia, Antiorthostatic,Antiorthostatic Hypokinesia,Antiorthostatic Hypokinesias,Bradykinesias,Hypokinesias, Antiorthostatic
D018482	Muscle, Skeletal	A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.	Anterior Tibial Muscle,Gastrocnemius Muscle,Muscle, Voluntary,Plantaris Muscle,Skeletal Muscle,Soleus Muscle,Muscle, Anterior Tibial,Muscle, Gastrocnemius,Muscle, Plantaris,Muscle, Soleus,Muscles, Skeletal,Muscles, Voluntary,Skeletal Muscles,Tibial Muscle, Anterior,Voluntary Muscle,Voluntary Muscles