-transparent.png){kind=logo}
From 1969--1975 patients with predominantly megakaryocytic myelosis were observed. Diagnosis was made up after histologic examination of iliac crest bone biopsy specimens embedded in methacrylate. From 6 patients rebiopsies and from further eleven ones the removed spleens were available. Autopsy was performed in 12 cases. In our material predominantly megakaryocytic myelosis was especially observed in male patients of advanced ages. The course of the disease was rarely acute, most often chronic and associated with the development of an extreme splenomegaly. Transition into osteomyelofibrosis or osteomyelosclerosis was frequent, the latter condition tended to develop a so-called myelosarcoma. The cause of death often was a generalized hemorrhagic diathesis with gastrointestinal hemorrhage or an fatal infection.
R Schäfer, and
H M Schueider, and
K Hill
June 1977,
Deutsche medizinische Wochenschrift (1946),
R Schäfer, and
H M Schueider, and
K Hill
October 1975,
Medizinische Klinik,
R Schäfer, and
H M Schueider, and
K Hill
January 1967,
The Medical journal of Australia,
R Schäfer, and
H M Schueider, and
K Hill
June 1976,
Journal of the American Veterinary Medical Association,
R Schäfer, and
H M Schueider, and
K Hill
July 1946,
Archives of internal medicine (Chicago, Ill. : 1908),
R Schäfer, and
H M Schueider, and
K Hill
January 1975,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
R Schäfer, and
H M Schueider, and
K Hill
November 1980,
American journal of clinical pathology,
R Schäfer, and
H M Schueider, and
K Hill
January 1956,
Le Sang,
R Schäfer, and
H M Schueider, and
K Hill
May 1973,
Acta pathologica japonica,
R Schäfer, and
H M Schueider, and
K Hill
May 1977,
Fortschritte der Medizin,
