-transparent.png){kind=logo}
Peroxisomes are capable of oxidizing a variety of substrates including (poly)unsaturated enoyl-CoA esters. The beta-oxidation of unsaturated enoyl-CoA esters in peroxisomes, and also in mitochondria, is not just chain-shortening but also involves the metabolizing of pre-existing carbon-to-carbon double bonds. In addition to the enzymes of the beta-oxidation spiral itself, this metabolism requires the participation of auxiliary enzymes: delta 3, delta 2-enoyl-CoA isomerase; 2,4-dienoyl-CoA reductase; 2-enoyl-CoA hydratase 2 or 3-hydroxyacyl-CoA epimerase; and delta 3,5 delta 2,4-dienoyl-CoA isomerase. Many of these enzymes are present as isoforms, and can be found located in multiple subcellular compartments, for example, peroxisomes, mitochondria or the endoplasmic reticulum, while some of the activities are integral parts of multifunctional enzymes of beta-oxidation systems.
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
June 1988,
Biochemical Society transactions,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 1981,
Methods in enzymology,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
December 1986,
The Journal of biological chemistry,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 1982,
Annals of the New York Academy of Sciences,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 1994,
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 1993,
Scandinavian journal of clinical and laboratory investigation. Supplementum,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 2001,
Doklady. Biochemistry and biophysics,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
August 1990,
The Biochemical journal,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
March 1979,
FEBS letters,
J K Hiltunen, and
S A Filppula, and
K T Koivuranta, and
K Siivari, and
Y M Qin, and
H M Häyrinen
January 1980,
Biochimica et biophysica acta,
