Biomaterial Database

Transcranial magnetic stimulation of the human frontal eye field. 1996

G W Thickbroom, and R Stell, and F L Mastaglia

Australian Neuromuscular Research Institute, Queen Elizabeth II Medical Centre, Nedlands, Australia. gthickbr@uniwa.uwa.edu.au

The region of cortex over which transcranial magnetic stimulation (TMS) can delay saccadic eye movement was investigated. With TMS delivered in the reaction time foreperiod of auditory-triggered saccades, saccade onset could be delayed by up to 60 ms. The area of cortex over which TMS could delay saccade onset was located near the inter-aural line, approximately 6 cm lateral to the vertex, and was situated between areas over which TMS could generate motor evoked potentials in muscles of the hand and face. It is concluded that this area corresponds to the human frontal eye field and is closely associated with the motor strip, at a level between the representations of the hand and the face, and that stimulation of this region can interfere with the programming and execution of externally triggered saccades.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D011930	Reaction Time	The time from the onset of a stimulus until a response is observed.	Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D005145	Face	The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.	Faces
D006225	Hand	The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.	Hands
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161	Acoustic Stimulation	Use of sound to elicit a response in the nervous system.	Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory