Halophilic vibrios (V. parahaemolyticus and V. alginolyticus) were for the first time isolated from the Azov sea in the Eisk district. These vibrios proved to be typical representatives of Vibrio genus and were distinctly differentiated by species according to the following signs: saccharose splitting, growth in peptone water with 10% NaCl solution, and acetylmethylcarbinol production. Swarming capacity on 1.5% agar with 3% NaCl proved to be a more variable sign. All the cultures isolated were typed by means of Japanese O- and K-sera and had the following antigenic formulae: O1:K32; O2:K28; O3:K57; O5:K17; O6:K18. Only in 3 cases it was impossible to determine completely the antigenic formula of vibrios referred by the O-antigen type +o the 7th and 11th groups. Thus, parahemolytic vibrios isolated from the Azov sea were referred to the serological types revealed in Japan in the sea water, hydrobionts and feces of patients with acute gastrointestinal diseases.