Biomaterial Database

Eosinophils in allergic reactions. 1996

P Desreumaux, and M Capron

Clinique des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, University Hospital, Lille, France.

Mainly located in the skin or mucosa of patients with allergic diseases, eosinophils contribute directly to tissue damage and chronic inflammation. The past year has seen significant advances in the study of the factors involved in the specific tissue recruitment of eosinophils, including chemoattractants and their receptors. New data have been obtained on the synthesis by eosinophils of various cytokines mostly released by immune complexes.

UI	MeSH Term	Description	Entries
D006967	Hypersensitivity	Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.	Allergy,Allergic Reaction,Allergic Reactions,Allergies,Hypersensitivities,Reaction, Allergic,Reactions, Allergic
D004804	Eosinophils	Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.	Eosinophil
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia