Genetic-environmental interactions in physical growth. 1977

R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein

Variability in stature among young children is often ascribed to health and nutrition differences in malnourished populations and to genetic differences in well-nourished populations. Hence, it was hypothesized that parent-child correlations in malnourished Guatemalan populations would be markedly lower than those reported for European samples. Instead, it was found that parent-child and sibling correlations were similar in both kinds of populations. The simplest interpretation of these results is that variability in stature among malnourished children is as much as reflection of genetic differences as in developed nations. However, explanations can also be advanced which would attribute the higher than expected correlations to the environment. For instance, it could be that socioeconomic and nutritional status is correlated across generations. In other words, parents who had relatively better conditions as children are more likely to provide a better environment for their children. Consequently, the relative contribution of genetics and environment to variability in height is still unsettled. Nonetheless, it appears that variability in body size in malnourished populations, regardless of the relative importance of its causes, is a useful indicator of health and nutrition.

UI MeSH Term Description Entries
D009748 Nutrition Disorders Disorders caused by nutritional imbalance, either overnutrition or undernutrition. Nutritional Disorders,Nutrition Disorder,Nutritional Disorder
D001827 Body Height The distance from the sole to the crown of the head with body standing on a flat surface and fully extended. Body Heights,Height, Body,Heights, Body
D002664 Child Nutritional Physiological Phenomena Nutritional physiology of children aged 2-12 years. Child Nutrition Physiology,Child Nutritional Physiology Phenomena,Nutrition Physiology, Child,Child Nutritional Physiology,Child Nutritional Physiology Phenomenon,Nutritional Physiology, Child,Physiology, Child Nutrition,Physiology, Child Nutritional
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003241 Consanguinity The magnitude of INBREEDING in humans. Inbreeding, Human,Consanguineous Marriage,Consanguinous Mating,Consanguineous Marriages,Consanguinities,Consanguinous Matings,Human Inbreeding,Human Inbreedings,Inbreedings, Human,Marriage, Consanguineous,Marriages, Consanguineous,Mating, Consanguinous,Matings, Consanguinous
D005828 Genetics, Population The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES. Population Genetics
D006128 Growth Gradual increase in the number, the size, and the complexity of cells of an individual. Growth generally results in increase in ORGAN WEIGHT; BODY WEIGHT; and BODY HEIGHT.
D006166 Guatemala A country in CENTRAL AMERICA bordering the North Pacific Ocean, between EL SALVADOR and MEXICO, and bordering the Gulf of Honduras (Caribbean Sea) between HONDURAS and BELIZE.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012959 Socioeconomic Factors Social and economic factors that characterize the individual or group within the social structure. Economic and Social Factors,Social Inequalities,Social Inequality,Social and Economic Factors,Socioeconomic Characteristics,Factors, Socioeconomic,High-Income Population,Land Tenure,Standard of Living,Characteristic, Socioeconomic,Factor, Socioeconomic,High Income Population,High-Income Populations,Inequality, Social,Living Standard,Living Standards,Population, High-Income,Socioeconomic Characteristic,Socioeconomic Factor,Tenure, Land

Related Publications

R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
October 1970, Transactions & studies of the College of Physicians of Philadelphia,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
October 1977, Cancer,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
March 1986, International journal of epidemiology,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
January 2003, The Journal of neuropsychiatry and clinical neurosciences,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
October 2001, Annales de chirurgie plastique et esthetique,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
January 1979, Progress in clinical and biological research,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
March 1954, Nutrition reviews,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
November 2023, Genes,
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
February 1997, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP),
R Martorell, and C Yarbrough, and A Lechtig, and H Delgado, and R E Klein
September 2006, Neurotoxicology,
Copied contents to your clipboard!