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Clinical electrocochleography in the diagnosis and management of Meneère's disorder. 1977

W P Gibson, and D A Moffat, and R T Ramsden

Patients with a fluctuating hearing loss, episodic vertigo and tinnitus with no known aetiological cause were investigated as cases of Menière's disorder. Transtympanic electrocochleography was found to be helpful in reaching the diagnosis of an inner ear disorder. In 65% of the patients, a large DC potential was recorded which caused an apparent widening of the summating potential/action potential (SP/AP) waveform. This potential was thought to be an SP which enhanced relative to the AP component, and believed to be related directly to the presence of endolymphatic hydrops. A method is described which 'scores' the clinical history with respect to certainty of the diagnosis of Meieère's disorder. It was found that the more certain cases, with high scores, were statistically more likely to show an abnormal SP/AP waveform. The results of endolymphatic sac surgery were also assessed over 1 year in 28 cases, and it was found that those patients whose ECochG had revealed an abnormal SP/AP waveform prior to surgery benefitted in a statistically significant manner more from the operation.

UI MeSH Term Description Entries
D008575 Meniere Disease A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops. Meniere's Disease,Meniere's Syndrome,Vertigo, Aural,Auditory Vertigo,Aural Vertigo,Ménière Disease,Ménière's Disease,Ménière's Vertigo,Otogenic Vertigo,Auditory Vertigos,Disease, Meniere,Disease, Meniere's,Disease, Ménière,Disease, Ménière's,Diseases, Ménière,Diseases, Ménière's,Meniere Syndrome,Menieres Disease,Menieres Syndrome,Ménière Diseases,Ménière Vertigo,Ménière's Diseases,Ménière's Vertigos,Ménières Disease,Ménières Vertigo,Otogenic Vertigos,Syndrome, Meniere's,Vertigo, Auditory,Vertigo, Ménière's,Vertigo, Otogenic,Vertigos, Auditory,Vertigos, Ménière's,Vertigos, Otogenic
D003056 Cochlear Nerve The cochlear part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The cochlear nerve fibers originate from neurons of the SPIRAL GANGLION and project peripherally to cochlear hair cells and centrally to the cochlear nuclei (COCHLEAR NUCLEUS) of the BRAIN STEM. They mediate the sense of hearing. Acoustic Nerve,Auditory Nerve,Acoustic Nerves,Auditory Nerves,Cochlear Nerves,Nerve, Acoustic,Nerve, Auditory,Nerve, Cochlear,Nerves, Acoustic,Nerves, Auditory,Nerves, Cochlear
D003638 Deafness A general term for the complete loss of the ability to hear from both ears. Deafness Permanent,Hearing Loss Permanent,Prelingual Deafness,Deaf Mutism,Deaf-Mutism,Deafness, Acquired,Hearing Loss, Complete,Hearing Loss, Extreme,Acquired Deafness,Complete Hearing Loss,Deafness, Prelingual,Extreme Hearing Loss,Permanent, Deafness,Permanent, Hearing Loss,Permanents, Deafness
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000200 Action Potentials Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli. Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D012444 Saccule and Utricle Two membranous sacs within the vestibular labyrinth of the INNER EAR. The saccule communicates with COCHLEAR DUCT through the ductus reuniens, and communicates with utricle through the utriculosaccular duct from which the ENDOLYMPHATIC DUCT arises. The utricle and saccule have sensory areas (acoustic maculae) which are innervated by the VESTIBULAR NERVE. Otolithic Organs,Utricle,Saccule,Organ, Otolithic,Otolithic Organ,Saccules,Utricle and Saccule,Utricles
D014012 Tinnitus A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions. Pulsatile Tinnitus,Ringing-Buzzing-Tinnitus,Spontaneous Oto-Acoustic Emission Tinnitus,Tensor Palatini Induced Tinnitus,Tensor Tympani Induced Tinnitus,Tinnitus of Vascular Origin,Tinnitus, Clicking,Tinnitus, Leudet,Tinnitus, Leudet's,Tinnitus, Noise Induced,Tinnitus, Objective,Tinnitus, Spontaneous Oto-Acoustic Emission,Tinnitus, Subjective,Tinnitus, Tensor Palatini Induced,Tinnitus, Tensor Tympani Induced,Vascular Origin Tinnitus,Clicking Tinnitus,Induced Tinnitus, Noise,Leudet Tinnitus,Leudet's Tinnitus,Noise Induced Tinnitus,Objective Tinnitus,Ringing Buzzing Tinnitus,Spontaneous Oto Acoustic Emission Tinnitus,Subjective Tinnitus,Tinnitus, Leudets,Tinnitus, Pulsatile,Tinnitus, Spontaneous Oto Acoustic Emission,Tinnitus, Vascular Origin

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