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During the period between December 1988 and February 1995, a total of 279,482 newborn infants were screened in the regional neonatal screening program for congenital hypothyroidism (CH) in Riyadh province, Saudi Arabia. Eighty-one infants were confirmed to have CH giving an incidence of 1 in 3,450. Variable congenital anomalies, other than those of the thyroid gland, were present in 16 (19.8%). The anomalies most frequently encountered were congenital heart defects (7), unclassified multiple congenital anomalies (5) and Down's syndrome (2). The results of our study confirm this association, and emphasize the need to search for such anomalies in infants born with CH. Nationwide studies, however, on birth defects in the general population and those associated with CH are still needed to help us understanding the role of local genetic and environmental factors.
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
January 1999,
Annales de genetique,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
June 1986,
Archives of disease in childhood,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
November 1986,
Archives of disease in childhood,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
November 2019,
BMC pediatrics,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
September 2012,
Oman medical journal,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
November 1983,
Indian pediatrics,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
August 2011,
Therapeutic advances in endocrinology and metabolism,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
October 2012,
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
December 1992,
Chest,
N A Al-Jurayyan, and
A S Al-Herbish, and
M I El-Desouki, and
A A Al-Nuaim, and
A M Abo-Bakr, and
M A Al-Husain
December 1996,
Prenatal diagnosis,
