Biomaterial Database

Morphological and histochemical changes in the liver of albino Wistar rat given flupenthixol depot. 1996

I Kasacka

Department of Histology and Embriology, Medical Academy of Białystok.

Histological findings and histoenzymatic reactions have shown that Flupenthixol Depot (FPX dep.) injected to rats in therapeutic doses induced morphologically observable degenerative lesions in the liver. No significant difference in the intensity of the lesions between the groups of male and female animals was found.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D008297	Male		Males
D010744	Phosphoric Monoester Hydrolases	A group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate.	Phosphatase,Phosphatases,Phosphohydrolase,Phosphohydrolases,Phosphomonoesterase,Phosphomonoesterases,Phosphoric Monoester Hydrolase,Hydrolase, Phosphoric Monoester,Hydrolases, Phosphoric Monoester,Monoester Hydrolase, Phosphoric
D002467	Cell Nucleus	Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)	Cell Nuclei,Nuclei, Cell,Nucleus, Cell
D003593	Cytoplasm	The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)	Protoplasm,Cytoplasms,Protoplasms
D005260	Female		Females
D005475	Flupenthixol	A thioxanthene neuroleptic that, unlike CHLORPROMAZINE, is claimed to have CNS-activating properties. It is used in the treatment of psychoses although not in excited or manic patients. (From Martindale, The Extra Pharmacopoeia, 30th ed, p595)	Emergil,Fluanxol,Flupentixol,alpha-Flupenthixol,cis-Flupenthixol
D006003	Glycogen
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014149	Tranquilizing Agents	A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes.	Ataractics,Tranquilizing Drugs,Tranquilizing Effect,Tranquilizing Effects,Tranquillizing Agents,Tranquillizing Drugs,Agents, Tranquilizing,Agents, Tranquillizing,Drugs, Tranquilizing,Drugs, Tranquillizing,Effect, Tranquilizing,Effects, Tranquilizing

Related Publications

I Kasacka

Age changes in the Wistar albino rat eye.

December 1951, American journal of ophthalmology,

I Kasacka

[Morphological and histochemical changes in the rat liver in chronic furfural poisoning].

January 1977, Medycyna pracy,

I Kasacka

[Morphological and histochemical changes in rat liver in subacute Phoschlor poisoning].

January 1976, Patologia polska,

I Kasacka

Histopathological changes in the liver and kidney tissues of Wistar albino rat exposed to fenitrothion.

October 2008, Toxicology and industrial health,

I Kasacka

[Morphological and histochemical studies of the galactose cataract of the albino rat].

July 1965, Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,

I Kasacka

[Morphological and histochemical changes in congestive liver].

January 1977, Patologia polska,

I Kasacka

[Morphological and histochemical changes in liver in pancreatitis].

December 1976, Sovetskaia meditsina,

I Kasacka

The ventral lateral geniculate nucleus of the albino rat morphological and histochemical observations.

January 1984, Journal fur Hirnforschung,

I Kasacka

[Age dependent histochemical changes in the thymus of the Wistar rat].

January 1970, Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948),