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Synthesis of 7-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)daunomycinone, a functional analog of daunorubicin.
1977
E F Fuchs, and D Horton, and W Weckerle
Associated MeSH Terms
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UI
MeSH Term
Description
Entries
D008722
Methods
A series of steps taken in order to conduct research.
Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D003630
Daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
Daunomycin,Rubidomycin,Rubomycin,Cerubidine,Dauno-Rubidomycine,Daunoblastin,Daunoblastine,Daunorubicin Hydrochloride,NSC-82151,Dauno Rubidomycine,Hydrochloride, Daunorubicin,NSC 82151,NSC82151
Related Publications
E F Fuchs, and D Horton, and W Weckerle
Synthesis of 2,6-dideoxy-alpha-L-lyxo- and 2,6-dideoxy-alpha-L-arabino-hexopyranosyl halides.
September 1977, Carbohydrate research,
E F Fuchs, and D Horton, and W Weckerle
Synthesis and antitumor activity of 7-O-(3,4-di-O-acetyl-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)adriamycinone.
July 1981, Carbohydrate research,
E F Fuchs, and D Horton, and W Weckerle
14-esters of 7-O-(3,4-di-O-acetyl-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)adriamycinone: synthesis and antitumor activity.
September 1983, The Journal of antibiotics,
E F Fuchs, and D Horton, and W Weckerle
A 5'-(trifluoromethyl)anthracycline glycoside: synthesis of antitumor-active 7-O-(2,6-dideoxy-6,6,6-trifluoro-alpha-L-lyxo-hexopyranosyl) adriamycinone.
April 1996, Journal of medicinal chemistry,
E F Fuchs, and D Horton, and W Weckerle
Design, synthesis and biological activity of 7-O-(4-O-acetyl-3-iodo-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl) daunomycinone and 7-O-(3-chloro-2,3,6-trideoxy-4-O-propanoyl-alpha-L-lyxo- hexopyranosyl)daunomycinone.
January 2000, Chemical & pharmaceutical bulletin,
E F Fuchs, and D Horton, and W Weckerle
7-O-(3-Amino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)daunomycinone, a configurational analog of daunorubicin.
November 1979, Carbohydrate research,
E F Fuchs, and D Horton, and W Weckerle
New adriamycin analogs. Synthesis and antitumor activity of 14-substituted 7-O-(3,4-di-O-acetyl-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)daunomycinones.
August 1981, The Journal of antibiotics,
E F Fuchs, and D Horton, and W Weckerle
Synthesis of antitumor-active 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.
November 1987, Carbohydrate research,
E F Fuchs, and D Horton, and W Weckerle
Synthesis of 7-O-[2,6-dideoxy-2-fluoro-4-O-(3-fluorotetrahydropyran-2-yl)- alpha-L-talopyranosyl]daunomycinone.
March 1992, The Journal of antibiotics,
E F Fuchs, and D Horton, and W Weckerle
Syntheses and antitumor activities of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.
May 1986, The Journal of antibiotics,
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