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1. In six patients arterial plasma lithium concentration-time curves were recorded following injection of lithium chloride into the right or left atrium. 2. Lognormal curve fitting was used to derive the areas under the first pass dilution curves. 3. Subjecting the curves produced by left atrial injection to a delay and sequential filtering produced curves that closely approximated those produced by right atrial injection. 4. We conclude that the transfer function of the right heart and lungs is equivalent to a delay and sequential filtering, that the primary indicator dilution curve is closely approximated by a lognormal curve and that loss of lithium in the lungs following right atrial injection is clinically insignificant.
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
March 1975,
Biomedical engineering,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
January 1963,
IEEE transactions on bio-medical engineering,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
March 1976,
British journal of anaesthesia,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
October 1989,
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D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
September 1961,
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D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
February 1979,
IEEE transactions on bio-medical engineering,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
June 1968,
Circulation research,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
January 1964,
Anesthesiology,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
January 1968,
Coeur et medecine interne,
D M Band, and
R A Linton, and
T K O'Brien, and
M M Jonas, and
N W Linton
March 1968,
Journal of applied physiology,
