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The paper presents a comparative study covering toxicological characteristics of benznthrone, brombenzanthrone, dibrombenzanthrone, methoxybenzanthrone, dibenzanronyl, dibenanthrone (violanthrone). The mentioned compounds were found to have a low acute and marked subchronic toxicity manifesting itself in the damaging action on the blood and liver. Here the reaction of the lympho-histiocytic elements along with the appearance of plasmatic and mast cells is typical. In the series of the study compounds most toxic are benzanthrone and its bromine-derivatives. Incorporation of a methoxy-group in the benzanthrone molecule and conjugation of two benzanthrone molecules help lessen the toxic action.
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
December 1950,
The Journal of biological chemistry,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1964,
Farmakologiia i toksikologiia,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1962,
Farmatsevtychnyi zhurnal,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1960,
Thorax,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
October 2002,
International journal of antimicrobial agents,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1960,
Farmakologiia i toksikologiia,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1946,
Farmakologiia i toksikologiia,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1957,
Farmakologiia i toksikologiia,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 1962,
Strahlentherapie,
V A Volodchenko, and
E R Sadokha, and
I S Ostrovskaiai, and
L V Timoshenko
January 2015,
Journal of oleo science,
