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The raw material of tocopherol acetate was tested for the preparation of the "Tocopherol Acetate Reference Standard (Control 941)". Analytical data obtained were as follows: infrared spectrum, the same as that of the Tocopherol Acetate Reference Standard (Control 919); specific absorbance, E1(1%)cm (284nm) = 44.5; thin-layer chromatography, no impurities were detected until 50.0 micrograms; high-performance liquid chromatography (HPLC), 2-3 impurities were detected and the amount was estimated to be about 1%; assay by HPLC, 100.8%. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Reference Standard (Control 941).
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