BIOMAT Database Logo BIOMAT Database Logo

beta-globin mRNA in Ferrara betao-thalassaemia. 1977

B G Forget, and D G Hillman

UI MeSH Term Description Entries
D005796 Genes A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms. Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D005914 Globins A superfamily of proteins containing the globin fold which is composed of 6-8 alpha helices arranged in a characterstic HEME enclosing structure. Globin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001483 Base Sequence The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence. DNA Sequence,Nucleotide Sequence,RNA Sequence,DNA Sequences,Base Sequences,Nucleotide Sequences,RNA Sequences,Sequence, Base,Sequence, DNA,Sequence, Nucleotide,Sequence, RNA,Sequences, Base,Sequences, DNA,Sequences, Nucleotide,Sequences, RNA
D012333 RNA, Messenger RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm. Messenger RNA,Messenger RNA, Polyadenylated,Poly(A) Tail,Poly(A)+ RNA,Poly(A)+ mRNA,RNA, Messenger, Polyadenylated,RNA, Polyadenylated,mRNA,mRNA, Non-Polyadenylated,mRNA, Polyadenylated,Non-Polyadenylated mRNA,Poly(A) RNA,Polyadenylated mRNA,Non Polyadenylated mRNA,Polyadenylated Messenger RNA,Polyadenylated RNA,RNA, Polyadenylated Messenger,mRNA, Non Polyadenylated
D013789 Thalassemia A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. Thalassemias

Related Publications

B G Forget, and D G Hillman
Direct demonstration of beta-globin mRNA in homozygous Ferrara betaO-thalassaemia patients.
March 1977, Nature,
B G Forget, and D G Hillman
Abnormal or absent beta mRNA in betao Ferrara and gene deletion in delta beta thalassaemia.
October 1976, Nature,
B G Forget, and D G Hillman
Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia.
July 1977, Proceedings of the National Academy of Sciences of the United States of America,
B G Forget, and D G Hillman
Decay of beta-globin synthesis in heterozygous beta (0) Ferrara thalassaemia.
October 1982, Haematologica,
B G Forget, and D G Hillman
Induction of -globin synthesis in the -thalassaemia of Ferrara.
July 1972, Nature: New biology,
B G Forget, and D G Hillman
beta-Globin messenger RNA in Ferrara beta 0 thalassemia.
January 1980, Annals of the New York Academy of Sciences,
B G Forget, and D G Hillman
Decreased beta globin mRNA activity in bone marrow cells in homozygous and heterozygous beta thalassaemia.
August 1973, Nature: New biology,
B G Forget, and D G Hillman
Ferrara beta 0 thalassaemia caused by the beta 39 nonsense mutation.
January 1984, Nature,
B G Forget, and D G Hillman
Globin chain synthesis in Ferrara and Sicilian beta-thalassemic subjects.
January 1970, Bulletin de la Societe de chimie biologique,
B G Forget, and D G Hillman
Variations in globin synthesis in delta-beta-thalassaemia.
January 1978, British journal of haematology,
Copied contents to your clipboard!