Surgical margins for soft tissue sarcoma. 1997

A Rydholm
Department of Orthopedics, University Hospital, Lund, Sweden. anders.rydholm@ort.lu.se

The Enneking classification of surgical margins is the only one which shows a reasonable correlation between the type of margin and the risk of local recurrence. However, it can be improved by a complementary definition of compartments and a better investigation of local tumor growth. Thus, if no open biopsy has been performed, a single muscle or a group of muscles, may constitute a compartment. Secondly, tumor growth at the border between the gross tumor and surrounding tissues should be better studied and classified. If preoperative radiotherapy is preferred, hopefully, growth patterns can be correlated with preoperative MR-findings to select patients who would benefit from radiotherapy combined with surgery. If postoperative radiotherapy is preferred, the operative specimen should be used for a microscopic classification of the tumor growth at the border, to make it possible to select only patients who need postoperative radiotherapy. Thus, it may be possible to combine Enneking's margins with a classification of tumor growth at the border, which permits a still better prognostication of local recurrence.

UI MeSH Term Description Entries
D009364 Neoplasm Recurrence, Local The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site. Local Neoplasm Recurrence,Local Neoplasm Recurrences,Locoregional Neoplasm Recurrence,Neoplasm Recurrence, Locoregional,Neoplasm Recurrences, Local,Recurrence, Local Neoplasm,Recurrence, Locoregional Neoplasm,Recurrences, Local Neoplasm,Locoregional Neoplasm Recurrences,Neoplasm Recurrences, Locoregional,Recurrences, Locoregional Neoplasm
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012509 Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. Sarcoma, Epithelioid,Sarcoma, Soft Tissue,Sarcoma, Spindle Cell,Epithelioid Sarcoma,Epithelioid Sarcomas,Sarcomas,Sarcomas, Epithelioid,Sarcomas, Soft Tissue,Sarcomas, Spindle Cell,Soft Tissue Sarcoma,Soft Tissue Sarcomas,Spindle Cell Sarcoma,Spindle Cell Sarcomas
D012983 Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. Neoplasm, Soft Tissue,Neoplasms, Soft Tissue,Soft Tissue Neoplasm
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