[Prenatal diagnosis of malformative uropathies: multicentric retrospective study and a proposed feto-neonatal diagnostic protocol]. 1996

L Pavanello, and M Pitter
Divisione di Pediatria-Ospedale di Castelfranco Veneto, Italia.

We have wanted to appraise the diagnostic reliability of fetal ultrasonography (FU) and its correlation with postnatal ultrasonography (PU). For two years we have studied 20.506 children born in 12 Pediatric Division of Veneto, all provided with FU. Between the 23rd and the 40th week of gestation the FU has individualized 177 fetuses with pelvic dilatation. The PU, performed in the 2nd and 7th day of life and then repeated to 1 month of life, has confirmed the prenatal diagnosis in 150 of the 247 renal unities, we have observed the 39% of false positive and the 8% of false negative. The sensibility has been 94%, specificity of 46%. The definitive diagnosis was: mild pelvic ectasia in 45%, ureteropelvic junction stenosis in 26%, vescicoureteric reflux in 15%, duplication of the renal collecting system and primary megaureter in 3%, multicystic kidneys and urethral valves in 5%. 20 children have been submitted to surgical corrective intervention. From the correlation performed between the entity of pelvic dilatation to the FU and to the PU we think it advisable to submit all the fetuses that show a caliceal dilation of > 5 mm to two ultrasounds, the first one between the 2nd-5th day of life and the second one at 30 days of life. In the newborn with caliceal dilatation of > 10 mm a micturating cystogram must be performed and subsequently in case of vescico ureteric reflux a DMSA scan is advisable, while in absence of reflux a DTPA scan or MAG3 scan is necessary. The renal pelvis with a diameter between 5-10 mm will perform ultrasound controls only each three months, unless there are partial or total reductions of the renal parenchymal, dilatation of the calices and/or the ureters.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002985 Clinical Protocols Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy. Protocols, Clinical,Research Protocols, Clinical,Treatment Protocols,Clinical Protocol,Clinical Research Protocol,Clinical Research Protocols,Protocol, Clinical,Protocol, Clinical Research,Protocols, Clinical Research,Protocols, Treatment,Research Protocol, Clinical,Treatment Protocol
D005260 Female Females
D005315 Fetal Diseases Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES. Embryopathies,Disease, Fetal,Diseases, Fetal,Embryopathy,Fetal Disease
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D014551 Urinary Tract The duct which coveys URINE from the pelvis of the KIDNEY through the URETERS, BLADDER, and URETHRA. Tract, Urinary,Tracts, Urinary,Urinary Tracts

Related Publications

L Pavanello, and M Pitter
January 1996, La Pediatria medica e chirurgica : Medical and surgical pediatrics,
L Pavanello, and M Pitter
January 1996, La Pediatria medica e chirurgica : Medical and surgical pediatrics,
L Pavanello, and M Pitter
February 2000, La Tunisie medicale,
L Pavanello, and M Pitter
December 2002, Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie,
L Pavanello, and M Pitter
March 1984, Journal de genetique humaine,
L Pavanello, and M Pitter
January 1983, Journal d'urologie,
L Pavanello, and M Pitter
March 2011, Transplantation proceedings,
L Pavanello, and M Pitter
February 1962, Medicina interna,
L Pavanello, and M Pitter
January 1989, Fetal therapy,
L Pavanello, and M Pitter
May 1988, Archivos espanoles de urologia,
Copied contents to your clipboard!