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BACKGROUND Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is known to be a contact sensitizer. It is used extensively in cosmetic products in low concentrations. Occupational exposure usually occurs with concentrated solutions and results in a different reaction pattern. RESULTS Three workers developed chemical burns and subsequent sensitization after exposure to concentrated solutions of MCI/MI. One patient was also occupationally sensitized to methyldibromoglutaronitrile/phenoxyethanol. CONCLUSIONS Exposure to concentrated solutions of some allergens can be severely irritating in the occupational setting and can probably induce sensitization.
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