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224 cases of fistula carcinoma arising from chronic osteomyelitis from literature and 6 own observations are reviewed. This malignancy results in about 1,5% cases of chronic osteomyelitis. The mean age of all patients was 55.7 years. The sex relation male to female was 7.4:1. The time from the beginning of the chronic osteomyelitis up to the diagnosis of the fistula carcinoma was 33.6 years. This time is called "Exposition time". The analysis of this time shows that, the older the patient was at the beginning of the chronic osteomyelitis the shorter was the exposition time.
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