Biomaterial Database

[Effects of halogenated hydrocarbons on polarographic measurement of oxygen partial pressure (author's transl)]. 1977

K Stosseck

Halothane can be reduced polarographically. The presence of halothane in a probe therefore may lead to an erroneous determination of oxygen partial pressure with a greater or less overestimation of the actual oxygen tension. In this study we report extent to which halothane influences the polarographic determination of oxygen tension in blood samples and in the transcutaneous determination of arterial oxygen tension. A clear dependence on halothane concentration was found concerning the transcutaneous measurement of oxygen tension, while measurement of oxygen tension in blood samples by means of the Combianalysator (Fa. Eschweiler, Kiel) was not affected by halothane. The different effect of halothane on the oxygen measurement is apperantly due to the size of the polarizing voltage. Below values of 500 to 600 mV halothane is practically not reduced, whereas above this range reduction takes place which results in an additional polarizing current superimposing the signal of the reduction of oxygen.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D010313	Partial Pressure	The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Partial Pressures,Pressure, Partial,Pressures, Partial
D011048	Polarography	An electrochemical technique for measuring the current that flows in solution as a function of an applied voltage. The observed polarographic wave, resulting from the electrochemical response, depends on the way voltage is applied (linear sweep or differential pulse) and the type of electrode used. Usually a mercury drop electrode is used.	DC Polarography,Pulse Polarography,Polarography, DC,Polarography, Pulse
D006221	Halothane	A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)	1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012867	Skin	The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.