[Chromatographic study of local anesthetics of the basic-ester type of substituted carbanilic acids. I. Use of Silufol and Lucefol for chromatographic separation].
1977
M Bachratá, and
M Blesová, and
Z Bezáková, and
A Lukás
UI
MeSH Term
Description
Entries
D002224
Carbanilides
Compounds consisting of two phenyl groups joined by a urea. Derivatives may be used as ANTIPARASITIC AGENTS.
Diphenylurea Compounds,Compounds, Diphenylurea
D002855
Chromatography, Thin Layer
Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.