The case of a patient with diffuse white furs in the whole esophagus is described. Esophagoscopy was suggestive of the presence of a wide-spread Candida esophagitis. The histologic and cultural examinations excluded Candida esophagitis and did not show unequivocal pathologic alterations. Detailed anamnestic exploration revealed a long existing distinct abuse of an antacid. After discontinuation of the antacid-intake a control gastroscopy was done 4 months later showing completely normal mucosa and disappearance of all furs. The present case demonstrates that antacidum intake must be encountered as differential diagnosis of esophageal white plaques.