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Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome. 1997
F Gianfrancesco, and
T Esposito, and
L Ruini, and
R Houlgatte, and
R Nagaraja, and
M D'Esposito, and
M Rocchi, and
C Auffray, and
D Schlessinger, and
M D'Urso, and
A Forabosco
International Institute of Genetics and Biophysics (IIGB), CNR, Naples, Italy.
The positioning of Expressed Sequence Tags (ESTs) constitutes an important step towards a functional map of the human genome, including candidate genes for human genetic disorders that have been localized by linkage analysis. We localized 59 ESTs on the human X chromosome, including 44 derived from infant brain and 15 from adult muscle cDNA libraries. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.
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