Self-regulation as the basic principle in the organization of living beings is analyzed from the viewpoint of the functional system theory for orthodox medicine and nonconventional therapies. Only some therapies in orthodox medicine are based on self-regulation whereas its role in nonconventional or traditional medicine is proposed to be more frequent and important. The paper describes how the similar principle can be clearly understood when the fundamental FST-principle (self-regulation) is used. The problems of the so-called vibrational medicine with its notion of a human being as a multidimensional organism made up of physical/cellular systems in a dynamic interplay with complex regulatory energy fields. Self-regulation is considered to be the crucial principle when subtle energetic medical approaches are applied as a cure. The paper also draws attention to informational processes in the body and its possible role in the mechanisms of orthodox and nonconventional therapies. The idea that the methods of traditional medicine have to be considered as complementary, but not alternative to orthodox, academic medicine is emphasized.