[Biology of lysogenic strains of Streptococcus bovis and virulent mutants of their temperate phages]. 1996

B V Tarakanov

Three lysogenic streptococcal strains and four virulent mutants of temperate phages were studied. The bacterial strains proved to be close to the type strain of Streptococcus bovis in their morphological, cultural, physiological, and biochemical properties. Investigation into the interaction of the lysogenic cultures with virulent mutants of temperate phages showed that the culture age optimal for infecting was 3-5 h; intense lysis began in the second hour after infection and was virtually completed by the end of the third hour, i.e., the procedure of obtaining phages in HMT medium took 7-8 h. Phage titers in phage lysates varied from 3.93 x 10(10) to 11.25 x 10(10) active phage particles per ml; residual amounts of viable bacteria varied from 0.7 x 10(6) to 34.0 x 10(6) cells per ml. In liquid HMT medium, phage production by lysogenic cultures was not limited by 0.3% glucose or maltose, 0.5% peptone, or casein hydrolysate. Descriptions of virulent mutants VM 6/6, VM 32/6, VM 28/28, and VM 54/54 of temperate phages of Str. bovis are presented.

UI MeSH Term Description Entries
D008242 Lysogeny The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium. Integration, Prophage,Prophage Integration,Integrations, Prophage,Prophage Integrations
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D001435 Bacteriophages Viruses whose hosts are bacterial cells. Phages,Bacteriophage,Phage
D014774 Virulence The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS. Pathogenicity
D016985 Streptococcus bovis A species of gram-positive, coccoid bacteria commonly found in the alimentary tract of cows, sheep, and other ruminants. It occasionally is encountered in cases of human endocarditis. This species is nonhemolytic. Streptococcus equinus

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