-transparent.png){kind=logo}
Three multicenter, randomized, double-blind, placebo-controlled studies were conducted to determine whether twelve weeks of therapy with itraconazole, 200 mg, was effective in the treatment of dermatophyte infection of the toenail. Significantly more patients treated with itraconazole (110 patients) than with placebo (104 patients) achieved clinical (65 percent vs. 3 percent) and mycologic (54 percent vs. 6 percent) success. The mean percentage of affected reference nail before the initiation of therapy was 76 percent. Adverse events were comparable in the two treatment groups. These findings demonstrate that twelve weeks of continuous itraconazole, 200 mg once daily, is a highly effective, well-tolerated therapy for the management of toenail onychomycosis.
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
August 1996,
International journal of dermatology,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
July 1996,
Journal of the American Academy of Dermatology,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
January 2000,
Acta dermato-venereologica,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
May 1999,
Acta dermato-venereologica,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
January 2006,
The Journal of dermatological treatment,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
January 1998,
Dermatology (Basel, Switzerland),
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
June 1996,
The British journal of dermatology,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
October 1995,
BMJ (Clinical research ed.),
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
March 2001,
Journal of the American Academy of Dermatology,
B E Elewski, and
R K Scher, and
R Aly, and
R Daniel, and
H E Jones, and
R B Odom, and
N Zaias, and
M L Jacko
May 1995,
Journal of the American Academy of Dermatology,
