-transparent.png){kind=logo}
A patient with chronic myelogenous leukemia who underwent transformation from the accelerated phase to the chronic phase with interferon-alpha treatment is reported. On admission, the numbers of myeloblasts and promyelocytes in the peripheral blood and bone marrow were 7.0% and 12.8%, respectively. The platelet count was 633.6 x 10(4)/microliter, and megakaryocytes were frequent in the bone marrow. In the accelerated phase, cytogenetic analyses revealed a hypotetraploid and a hypooctoploid cell population with two and four Philadelphia chromosomes, respectively, in the bone marrow specimen. The hypooctoploid clone disappeared with administration of interferon-alpha and the hypotetraploid clone also subsequently disappeared.
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
January 1984,
Diagnostic immunology,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
March 1948,
Archives of dermatology and syphilology,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
January 1997,
Oncology,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
September 2003,
Leukemia research,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
January 1991,
Leukemia & lymphoma,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
June 1967,
Archives of internal medicine,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
January 2019,
Transactions of the American Clinical and Climatological Association,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
March 2005,
Archives of pathology & laboratory medicine,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
February 1999,
Seminars in oncology,
T Shichishima, and
Y Hamazaki, and
R Abe, and
Y Shiga, and
T Abe, and
Y Maruyama
April 2000,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
