Isolation of a mammalian cell mutant resistant to 25-hydroxy cholesterol.
1977
M Sinensky
UI
MeSH Term
Description
Entries
D008798
Mevalonic Acid
A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions.
Mevalonate,Acid, Mevalonic
D009154
Mutation
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Mutations
D002460
Cell Line
Established cell cultures that have the potential to propagate indefinitely.
Cell Lines,Line, Cell,Lines, Cell
D002784
Cholesterol
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Epicholesterol
D002788
Cholesterol Esters
Fatty acid esters of cholesterol which constitute about two-thirds of the cholesterol in the plasma. The accumulation of cholesterol esters in the arterial intima is a characteristic feature of atherosclerosis.
Cholesterol which is substituted by a hydroxy group in any position.
D000085
Acetates
Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.