Dog-DAT: a direct agglutination test using stabilized, freeze-dried antigen for the serodiagnosis of canine visceral leishmaniasis. 1996

L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
Royal Tropical Institute, Department of Biomedical Research, Amsterdam, Netherlands. bo@mail.kit.support.nl

We have evaluated the use of an improved direct agglutination test (DAT) based on stable, freeze-dried antigen for the detection of anti-Leishmania antibodies in canine serum samples. With a cut-off value of 1:640, the sensitivity of the DAT was shown to be 100% and the specificity of the test was 98.8%.

UI MeSH Term Description Entries
D007898 Leishmaniasis, Visceral A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African. Black Fever,Kala-Azar,Fever, Black,Kala Azar,Visceral Leishmaniasis
D009426 Netherlands Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, and Sint Maarten, formerly included in the NETHERLANDS ANTILLES. Holland,Kingdom of the Netherlands
D004283 Dog Diseases Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used. Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D005069 Evaluation Studies as Topic Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D005612 Freeze Drying Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products. Lyophilization,Drying, Freeze,Dryings, Freeze,Freeze Dryings,Lyophilizations
D000372 Agglutination Tests Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed) Agglutination Test,Test, Agglutination,Tests, Agglutination
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000913 Antibodies, Protozoan Immunoglobulins produced in a response to PROTOZOAN ANTIGENS. Protozoan Antibodies
D000953 Antigens, Protozoan Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered. Protozoan Antigens

Related Publications

L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
July 1995, Journal of clinical microbiology,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
December 2006, Tropical medicine & international health : TM & IH,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
January 1991, Journal of clinical laboratory analysis,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
April 2020, The American journal of tropical medicine and hygiene,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
October 2004, Tropical medicine & international health : TM & IH,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
May 2016, Veterinary parasitology,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
July 2011, Transactions of the Royal Society of Tropical Medicine and Hygiene,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
December 2009, Transactions of the Royal Society of Tropical Medicine and Hygiene,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
October 1999, Annals of tropical medicine and parasitology,
L Oskam, and R J Slappendel, and E G Beijer, and N C Kroon, and C W van Ingen, and S Ozensoy, and Y Ozbel, and W J Terpstra
December 2000, La Tunisie medicale,
Copied contents to your clipboard!