[Role of lipid composition in the kinetics of free radical lipid oxidation in photoreceptor membranes]. 1977

K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan

The initial rate of lipid peroxidation (LPO) in photoreceptor membranes (PRM) of walleye pollock is 1.8--2.3 times higher than in frog PRM. Rhodopsin bleaching leads to an increase of LPO initial rate in PRM while having no effect on LPO in walleye pollack PRM. The content of unsaturated fatty acids in walleye pollock PRM is 1.4 times greater than in frog PRM. It is suggested that differences in LPO kinetics in PRM of walleye pollack and frog are caused by the differences in the lipid composition of the membranes (primarily by a high level of phospholipid molecular species with two unsaturated fatty acid residues in walleye pollock retina rod outer segments).

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D010545 Peroxides A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed) Peroxide
D010743 Phospholipids Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system. Phosphatides,Phospholipid
D010786 Photoreceptor Cells Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade. Ciliary Photoreceptor Cells,Ciliary Photoreceptors,Rhabdomeric Photoreceptor Cells,Rhabdomeric Photoreceptors,Cell, Ciliary Photoreceptor,Cell, Photoreceptor,Cell, Rhabdomeric Photoreceptor,Cells, Ciliary Photoreceptor,Cells, Photoreceptor,Cells, Rhabdomeric Photoreceptor,Ciliary Photoreceptor,Ciliary Photoreceptor Cell,Photoreceptor Cell,Photoreceptor Cell, Ciliary,Photoreceptor Cell, Rhabdomeric,Photoreceptor Cells, Ciliary,Photoreceptor Cells, Rhabdomeric,Photoreceptor, Ciliary,Photoreceptor, Rhabdomeric,Photoreceptors, Ciliary,Photoreceptors, Rhabdomeric,Rhabdomeric Photoreceptor,Rhabdomeric Photoreceptor Cell
D002462 Cell Membrane The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells. Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D002621 Chemistry A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
D005227 Fatty Acids Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed) Aliphatic Acid,Esterified Fatty Acid,Fatty Acid,Fatty Acids, Esterified,Fatty Acids, Saturated,Saturated Fatty Acid,Aliphatic Acids,Acid, Aliphatic,Acid, Esterified Fatty,Acid, Saturated Fatty,Esterified Fatty Acids,Fatty Acid, Esterified,Fatty Acid, Saturated,Saturated Fatty Acids
D005231 Fatty Acids, Unsaturated FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds. Fatty Acids, Polyunsaturated,Polyunsaturated Fatty Acid,Unsaturated Fatty Acid,Polyunsaturated Fatty Acids,Acid, Polyunsaturated Fatty,Acid, Unsaturated Fatty,Acids, Polyunsaturated Fatty,Acids, Unsaturated Fatty,Fatty Acid, Polyunsaturated,Fatty Acid, Unsaturated,Unsaturated Fatty Acids
D005399 Fishes A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D005609 Free Radicals Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated. Free Radical

Related Publications

K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
February 2005, Biochemistry,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
January 1976, Voprosy meditsinskoi khimii,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
December 1975, Biochimica et biophysica acta,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
January 1988, Vestnik Akademii meditsinskikh nauk SSSR,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
January 1987, Biofizika,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
January 1997, Urologiia i nefrologiia,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
March 1982, Toxicology and applied pharmacology,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
May 1970, Archives of biochemistry and biophysics,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
August 1998, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
K N Novikov, and A A Shvedova, and V A Tiurin, and S A Shukoliukov, and V E Kagan
March 1982, Kardiologiia,
Copied contents to your clipboard!