BIOMAT Database Logo BIOMAT Database Logo

Regional left ventricular contractile dynamics in hypertrophic cardiomyopathy evaluated by magnetic resonance imaging. 1996

T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Department of Cardiovascular Medicine, Okayama University, Japan.

To assess regional myocardial function in hypertrophic cardiomyopathy (HCM), we examined systolic wall thickening (%WT) and percent change of segmental wall area (%AR) by cine magnetic resonance imaging. We studied 23 normal volunteers without evidence of heart disease (group 1) and 40 patients with HCM (group 2). Short-axis images of the left ventricle were recorded at the base and the apex, and were divided into five segments. There were no significant differences in %WT and %AR among the segments in group 1, while %WT and %AR at the apex were higher than values for corresponding segments at the base. The patients with HCM (group 2) were classified into three groups according to end-diastolic wall thickness: group 2a, less than 12 mm; group 2b, 12-15 mm and group 2c, greater than 15 mm. Both the %WT and %AR at the base were significantly higher in group 2a than in the other groups, but were significantly lower in group 2c than in group 1 or group 2a (%WT and %AR in groups 1, 2a, 2b, and 2c respectively: 51 +/- 29 and 19 +/- 17; 83 +/- 40 and 34 +/- 18; 47 +/- 38 and 16 +/- 14; and 32 +/- 21 and 9 +/- 8). Both %WT (40 +/- 24) and %AR (14 +/- 12) at the apex were significantly lower in group 2c than in the other groups (87 +/- 45 and 38 +/- 31 in group 1; 89 +/- 41 and 39 +/- 31 in group 2a; and 61 +/- 27 and 24 +/- 15 in group 2b). Myocardial shortening in the normal volunteers was greater at the apex than at the base. In patients with HCM, regional myocardial function was decreased in association with the degree of hypertrophy, with the wall function of the normal segments appearing to be increased in a possible compensatory mechanism.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D002312 Cardiomyopathy, Hypertrophic A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY). Cardiomyopathy, Hypertrophic Obstructive,Cardiomyopathies, Hypertrophic,Cardiomyopathies, Hypertrophic Obstructive,Hypertrophic Cardiomyopathies,Hypertrophic Cardiomyopathy,Hypertrophic Obstructive Cardiomyopathies,Hypertrophic Obstructive Cardiomyopathy,Obstructive Cardiomyopathies, Hypertrophic,Obstructive Cardiomyopathy, Hypertrophic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D018487 Ventricular Dysfunction, Left A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. LV Diastolic Dysfunction,LV Dysfunction,LV Systolic Dysfunction,Left Ventricular Diastolic Dysfunction,Left Ventricular Dysfunction,Left Ventricular Systolic Dysfunction,Diastolic Dysfunction, LV,Dysfunction, LV,Dysfunction, LV Diastolic,Dysfunction, LV Systolic,Dysfunction, Left Ventricular,LV Diastolic Dysfunctions,LV Dysfunctions,LV Systolic Dysfunctions,Left Ventricular Dysfunctions,Systolic Dysfunction, LV
D019028 Magnetic Resonance Imaging, Cine A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized. Cine MRI,Cine Magnetic Resonance Imaging,Cine MRIs,MRI, Cine,MRIs, Cine

Related Publications

T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Detection of regional left ventricular asynchrony in obstructive hypertrophic cardiomyopathy by magnetic resonance imaging.
March 1994, American heart journal,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Functional assessment of left ventricular ejection dynamics by cine-magnetic resonance imaging in hypertrophic cardiomyopathy.
May 1994, The American journal of cardiology,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Magnetic resonance imaging of delayed enhancement in hypertrophic cardiomyopathy: relationship with left ventricular perfusion and contractile function.
January 2006, Journal of computer assisted tomography,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Magnetic resonance imaging of hypertrophic cardiomyopathy: beyond left ventricular wall thickness.
February 2015, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Left ventricular structure and diastolic function by cardiac magnetic resonance imaging in hypertrophic cardiomyopathy.
January 2018, Indian heart journal,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Left Ventricular Mass in Hypertrophic Cardiomyopathy Assessed by 2D-Echocardiography: Validation with Magnetic Resonance Imaging.
April 2020, Journal of cardiovascular translational research,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Regional left ventricular myocardial contraction abnormalities and asynchrony in patients with hypertrophic cardiomyopathy evaluated by magnetic resonance spatial modulation of magnetization myocardial tagging.
June 1999, Japanese circulation journal,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Magnetic resonance imaging of mid-ventricular obstructive hypertrophic cardiomyopathy.
September 2013, QJM : monthly journal of the Association of Physicians,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
Left Ventricular Apical Aneurysms in Hypertrophic Cardiomyopathy: Equivalent Detection by Magnetic Resonance Imaging and Contrast Echocardiography.
December 2021, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
T Sato, and H Yamanari, and T Ohe, and T Yoshinouchi
[Arrhythmogenic left ventricular cardiomyopathy: beyond magnetic resonance imaging].
July 2023, Giornale italiano di cardiologia (2006),
Copied contents to your clipboard!