Ovine placental lactogen induces somatomedin: a a possible role in fetal growth. 1977

T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows

Ovine placental lactogen (oPL) and bovine growth hormone (bGH) increase the circulating concentration of somatomedin in hypophysectomized rats. This finding indicates that some of the somatotropic properties of oPL may be due to the induction of somatomedin and raises the possibility that oPL has a role in the control of fetal growth.

UI MeSH Term Description Entries
D007016 Hypophysectomy Surgical removal or destruction of the hypophysis, or pituitary gland. (Dorland, 28th ed) Hypophysectomies
D010928 Placental Lactogen A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist. Choriomammotropin,Chorionic Somatomammotropin, Human,Human Placental Lactogen,Lactogen Hormone, Placental,Mammotropic Hormone, Placental,Somatomammotropin, Chorionic,Choriomammotrophin,HCS (Human Chorionic Somatomammotropin),HPL (Human Placental Lactogen),PAPP-D,Placental Luteotropin,Pregnancy-Associated Plasma Protein D,Chorionic Somatomammotropin,Human Chorionic Somatomammotropin,Lactogen, Placental,Luteotropin, Placental,Placental Lactogen, Human,Placental Mammotropic Hormone,Pregnancy Associated Plasma Protein D
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012756 Sheep Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS. Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D013002 Somatomedins Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism. Sulfation Factor,Somatomedin,Factor, Sulfation
D013006 Growth Hormone A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized. Growth Hormone, Recombinant,Pituitary Growth Hormone,Recombinant Growth Hormone,Somatotropin,Somatotropin, Recombinant,Growth Hormone, Pituitary,Growth Hormones Pituitary, Recombinant,Pituitary Growth Hormones, Recombinant,Recombinant Growth Hormones,Recombinant Pituitary Growth Hormones,Recombinant Somatotropins,Somatotropins, Recombinant,Growth Hormones, Recombinant,Recombinant Somatotropin
D013268 Stimulation, Chemical The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical. Chemical Stimulation,Chemical Stimulations,Stimulations, Chemical
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
February 1986, Endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
January 1984, The American journal of physiology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
November 1996, Domestic animal endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
January 1983, Endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
June 1988, The Journal of clinical endocrinology and metabolism,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
April 1985, Endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
August 1983, Journal of developmental physiology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
May 1978, Endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
September 1981, The Journal of endocrinology,
T W Hurley, and A J D'Ercole, and S Handwerger, and L E Underwood, and R W Furlanetto, and R E Fellows
May 1987, Endocrinology,
Copied contents to your clipboard!