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Conversion of the carcinogen n-acetoxy-2-acetamidofluorene to 4-hydroxy-2-acetamidofluorene.
1977
J D Scribner
Associated MeSH Terms
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UI
MeSH Term
Description
Entries
D005449
Fluorenes
A family of diphenylenemethane derivatives.
D006881
Hydroxyacetylaminofluorene
A N-hydroxylated derivative of 2-ACETYLAMINOFLUORENE that has demonstrated carcinogenic action.
Hydroxyfluorenylacetamide,N-Hydroxy-2-acetamidofluorene,N Hydroxy 2 acetamidofluorene
D000099
Acetoxyacetylaminofluorene
An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.
Acetoxyacetamidofluorene,Acetoxyfluorenylacetamide,N-Acetoxy-2-acetylaminofluorene,N-Acetoxy-N-acetyl-2-aminofluorene,N Acetoxy 2 acetylaminofluorene,N Acetoxy N acetyl 2 aminofluorene
Related Publications
J D Scribner
Antibodies to DNA modified by the carcinogen N-acetoxy-N-2-acetylaminofluorene.
August 1978, FEBS letters,
J D Scribner
On the metabolic activation of the carcinogen N-hydroxy-N-2-acetylaminofluorene. 3. Oxidation with horseradish peroxidase to yield 2-nitrosofluorene and N-acetoxy-N-2-acetylaminofluorene.
June 1971, Biochimica et biophysica acta,
J D Scribner
Interaction of nucleophiles with the enzymatically-activated carcinogen, N-hydroxy-2-acetylaminofluorene, and with the model ester, N-acetoxy-2-acetylaminofluorene.
February 1985, Carcinogenesis,
J D Scribner
In vitro covalent binding to DNA of the ultimate carcinogen N-acetoxy-N-4-acetylaminobiphenyl.
September 1977, FEBS letters,
J D Scribner
Reactivity of antibodies to guanosine modified by the carcinogen N-acetoxy-N-2-acetylaminofluorene.
February 1979, Nucleic acids research,
J D Scribner
Monoclonal antibodies to DNA modified by the carcinogen N-acetoxy-N-2 acetyl aminofluorene.
January 1984, Developments in biological standardization,
J D Scribner
Relative DNA damage induced in cultured human skin fibroblasts by exposure to the precarcinogen 2-acetylaminofluorene, the proximate carcinogen N-hydroxy-2-acetylaminofluorene, and the ultimate carcinogen N-acetoxy-2-acetylaminofluorene.
July 1973, Canadian journal of biochemistry,
J D Scribner
The conversion of the carcinogen N-hydroxy-2-fluorenylacetamide to o-amidophenols by rat liver in vitro.
February 1972, The Journal of biological chemistry,
J D Scribner
Dynamic structure of DNA modified with the carcinogen N-acetoxy-n-2-acetylaminofluorene.
October 1974, Biochemistry,
J D Scribner
Reactivity of the antibodies to DNA modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene.
April 1979, Biochemistry,
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