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We have improved the resolution of the conventional method for phenotyping deoxyribonuclease I (DNase I), which makes use of isoelectric focusing, by the addition of amphoteric separators. The distribution of DNase I phenotypes was extensively examined using this improved method in 1,212 unrelated individuals from a Japanese population. In order to investigate a possible difference in phenotype distribution between different populations, DNA samples from Germans and African Americans were genotyped using the polymerase chain reaction. The DNASE1*2 allele in the German population was found to be predominant among the four alleles of DNase I, in contrast to the Japanese population. These results are the first to demonstrate a wide distribution of DNase I polymorphism in the Japanese population as well as in two other populations.
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
February 1989,
Human genetics,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
October 1997,
Electrophoresis,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
January 1979,
Gastroenterologia Japonica,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
January 1980,
Gastroenterologia Japonica,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
November 1963,
Archives of biochemistry and biophysics,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
April 1980,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
February 2010,
International journal of immunogenetics,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
September 2008,
Molecular biology reports,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
January 2016,
Clinical rheumatology,
T Yasuda, and
H Takeshita, and
R Iida, and
I Yuasa, and
K Kishi
September 1990,
Journal of biochemistry,
