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Dahl-Iwai salt-sensitive (S) and salt-resistant (R) rat strains were established as inbred strains at Brookhaven National Laboratory, NY, and were introduced into Eisai Co., Ltd., Japan, and designated DIS/Eis and DIR/Eis. To examine whether there are different allele distributions among the substrains of inbred Dahl S and R rats, we determined biochemical and immunological alleles of DIS/Eis and DIR/Eis, and SS/Sea and SR/Sea, which were derived from SS/Jr and SR/Jr, which were developed by Rapp and Dene. Several differences of allele distribution were observed, indicating that the substrains have different genetic backgrounds. The phenotypic differences between the substrains, such as the severity of the hypertension induced, could be ascribed to the different genetic backgrounds.
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
May 1997,
American journal of hypertension,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
May 1997,
American journal of hypertension,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
January 1994,
Life sciences,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
May 1993,
Journal of hypertension,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
January 1999,
Journal of hypertension,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
October 1986,
Journal of hypertension. Supplement : official journal of the International Society of Hypertension,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
January 1996,
Hypertension (Dallas, Tex. : 1979),
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
January 1998,
Japanese heart journal,
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
January 1985,
Hypertension (Dallas, Tex. : 1979),
K Yamazaki, and
H Katoh, and
N Yamamoto, and
K Kurihara, and
M Kuwabara, and
M Kodama, and
A Kawaguchi, and
Y Funami, and
T Wakabayashi
May 1997,
American journal of hypertension,
