-transparent.png){kind=logo}
The interaction of a bioengineered serpin (LEX032) with human leukocyte proteinase 3 (PR 3) has been investigated. LEX032 was found to be a time-dependent inhibitor of PR 3, forming a highly-stable enzyme-inhibitor complex (Ki 12 nM).
Related Publications
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
October 1995,
Shock (Augusta, Ga.),
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
January 1991,
Annals of the New York Academy of Sciences,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
August 1998,
European journal of pharmacology,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
January 1998,
Journal of leukocyte biology,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
November 1993,
European journal of immunology,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
January 1998,
The Journal of biological chemistry,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
September 1999,
Biochimica et biophysica acta,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
February 1993,
The American review of respiratory disease,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
July 1999,
The Journal of biological chemistry,
W C Groutas, and
S Ruan, and
R Kuang, and
J B Hook, and
H Sands
December 2011,
Pharmacological research,
