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The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. 1997
H Tettelin, and
M L Agostoni Carbone, and
K Albermann, and
M Albers, and
J Arroyo, and
U Backes, and
T Barreiros, and
I Bertani, and
A J Bjourson, and
M Brückner, and
C V Bruschi, and
G Carignani, and
L Castagnoli, and
E Cerdan, and
M L Clemente, and
A Coblenz, and
M Coglievina, and
E Coissac, and
E Defoor, and
S Del Bino, and
H Delius, and
D Delneri, and
P de Wergifosse, and
B Dujon, and
K Kleine
Unité de Biochimie Physiologique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VII has 572 predicted open reading frames (ORFs), of which 341 are new. No correlation was found between G+C content and gene density along the chromosome, and their variations are random. Of the ORFs, 17% show high similarity to human proteins. Almost half of the ORFs could be classified in functional categories, and there is a slight increase in the number of transcription (7.0%) and translation (5.2%) factors when compared with the complete S. cerevisiae genome. Accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.
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