Effect of tumor promoting agents on mutation frequencies in cultured V79 Chinese hamster cells.
1977
G R Lankas, and
S Baxter, and
R T Christian
UI
MeSH Term
Description
Entries
D008769
Methylnitronitrosoguanidine
A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties.
Methylnitrosonitroguanidine,Nitrosomethylnitroguanidine,Nitrosonitromethylguanidine,MNNG,N-Methyl-N'-nitro-N-nitrosoguanidine,N Methyl N' nitro N nitrosoguanidine
D009154
Mutation
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Mutations
D002273
Carcinogens
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.