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Cytophotometric examinations of solid carcinomas of Ehrlich in mice don't show a considerable cyto-cinetic effect after administration of Vincristin. On the other hand, Adriamycin causes in the same tumor a significant stop in the G2 + M phase with a synchronization factor of 1,4 to 1,5 related to G2. The following experiment with the combined Adriamycin and radiotherapy demonstrates with a statistical significance lying about 5% that an immediate radiotherapeutic success can be obtained which is even increased by a partial synchronization. A considerably enriched G2 + M phase as a result of the administration of Adriamyzin is proven by a first cyto-cinetic examination of human cancerous tissue. A possible clinical therapy scheme is discussed.
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
January 1981,
Nephrologie,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
June 1975,
Deutsche medizinische Wochenschrift (1946),
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
March 1980,
EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
January 1975,
Wiener klinische Wochenschrift,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
July 1978,
Deutsche medizinische Wochenschrift (1946),
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
December 1977,
Deutsche medizinische Wochenschrift (1946),
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
April 1976,
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
October 1977,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
September 1980,
Klinische Wochenschrift,
E Esser, and
J Haut, and
J Schumann, and
M Wannenmacher, and
U Wingenfeld
April 1978,
Blut,
