[Venous leg ulcer]. 1997

B Hamilton Jakobsen, and L Danielsen
Kirurgisk speciallaegepraksis, Frederiksberg.

The article summarizes current views regarding venous leg ulcers. Venous ulcers are resource-demanding and affect 1% of the population. Superficial and/or deep venous insufficiency is to be found combined with perforator insufficiency in the ankle are. The pathogenesis is still open to debate, but is presumably related to capillary leakage, with seepage of blood components and ensuing lipodermatosclerosis, as well as to multiple capillary thromboses. Inappropriate leucocyte activation might also play a part. Compression stabilizes capillary function and thus is the cardinal treatment both regarding healing and prophylaxis. In 90% of cases there is no recurrence following superficial vein surgery, so long as the deep veins remain unaffected. In patients with deep venous insufficiency the risk of failure following-such surgery, perforator resection included, is related to the degree of insufficiency. If conventional treatment fails, reconstruction of the deep veins may be considered. Concomitant conditions such as arterial insufficiency and systemic diseases make treatment difficult, and the presence of Pseudomonas aeruginosa may in certain cases delay healing.

UI MeSH Term Description Entries
D007871 Leg Ulcer Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes. Leg Ulcers,Ulcer, Leg,Ulcers, Leg
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014647 Varicose Ulcer Skin breakdown or ulceration in the drainage area of a VARICOSE VEIN, usually in the leg. Stasis Ulcer,Venous Ulcer,Venous Hypertension Ulcers,Venous Stasis Ulcers,Hypertension Ulcer, Venous,Hypertension Ulcers, Venous,Stasis Ulcer, Venous,Stasis Ulcers,Stasis Ulcers, Venous,Ulcer, Stasis,Ulcer, Varicose,Ulcer, Venous,Ulcer, Venous Hypertension,Ulcer, Venous Stasis,Ulcers, Stasis,Ulcers, Varicose,Ulcers, Venous,Ulcers, Venous Hypertension,Ulcers, Venous Stasis,Varicose Ulcers,Venous Hypertension Ulcer,Venous Stasis Ulcer,Venous Ulcers

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