Biomaterial Database

A 48-month survival analysis comparing sealant (Delton) with fluoride varnish (Duraphat) in 6- to 8-year-old children. 1997

M Bravo, and I Garcia-Anllo, and P Baca, and J C Llodra

Department of Preventive Dentistry, School of Dentistry, University of Granada, Spain.

The objective of this study was to compare Delton visible-light fissure sealant with Duraphat fluoride varnish in the prevention of occlusal caries in permanent first molars. A 48-month clinical trial was carried out in three groups of 6- to 8-year-old schoolchildren: a sealant group (104 children), in which Delton was used; a varnish group (112 children), in which Duraphat was used; and a control group (128 children). Sealant or varnish was applied to all sound permanent first molars, according to group. Replacement (sealant) and reapplication (varnish) was carried out every 6 months. A survival analysis was used to describe the molar failures over time in the three groups. A Cox proportional hazards regression model was built to test the influence of group on molar failure. The median survival times were 28.6 months for the control molars and more than 48 months for both sealed and varnished molars. The Cox model indicated a hazard ratio of 0.177 for the sealant vs control comparison, 0.463 for varnish vs control and 0.382 for sealant vs varnish.

UI	MeSH Term	Description	Entries
D008137	Longitudinal Studies	Studies in which variables relating to an individual or group of individuals are assessed over a period of time.	Bogalusa Heart Study,California Teachers Study,Framingham Heart Study,Jackson Heart Study,Longitudinal Survey,Tuskegee Syphilis Study,Bogalusa Heart Studies,California Teachers Studies,Framingham Heart Studies,Heart Studies, Bogalusa,Heart Studies, Framingham,Heart Studies, Jackson,Heart Study, Bogalusa,Heart Study, Framingham,Heart Study, Jackson,Jackson Heart Studies,Longitudinal Study,Longitudinal Surveys,Studies, Bogalusa Heart,Studies, California Teachers,Studies, Jackson Heart,Studies, Longitudinal,Study, Bogalusa Heart,Study, California Teachers,Study, Longitudinal,Survey, Longitudinal,Surveys, Longitudinal,Syphilis Studies, Tuskegee,Syphilis Study, Tuskegee,Teachers Studies, California,Teachers Study, California,Tuskegee Syphilis Studies
D008963	Molar	The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)	Molars
D010895	Pit and Fissure Sealants	Agents used to occlude dental enamel pits and fissures in the prevention of dental caries.	Dental Sealant,Dental Sealants,Fissure Sealant,Fissure Sealants,Pit And Fissure Sealant,Pit Fissure Sealant,Sealants, Tooth,Pit Fissure Sealants,Sealants, Dental,Fissure Sealant, Pit,Fissure Sealants, Pit,Sealant, Dental,Sealant, Fissure,Sealant, Pit Fissure,Sealant, Tooth,Sealants, Fissure,Sealants, Pit Fissure,Tooth Sealant,Tooth Sealants
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003731	Dental Caries	Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.	Caries, Dental,Carious Lesions,Dental Cavities,Dental Cavity,Dental Decay,Dental White Spots,Carious Dentin,Decay, Dental,Dental White Spot,White Spot, Dental,White Spots, Dental,Carious Dentins,Carious Lesion,Cavities, Dental,Cavity, Dental,Dentin, Carious,Dentins, Carious,Lesion, Carious,Lesions, Carious,Spot, Dental White,Spots, Dental White
D004245	DMF Index	"Decayed, missing and filled teeth," a routinely used statistical concept in dentistry.	Decayed, Missing, and Filled Teeth,DMF Indexes,DMF Indexe,DMF Indices,Index, DMF,Indexe, DMF,Indexes, DMF,Indices, DMF
D005460	Fluorides, Topical	Fluorides, usually in pastes or gels, used for topical application to reduce the incidence of DENTAL CARIES.	Fluoride Varnishes,Topical Fluorides,Varnishes, Fluoride
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012969	Sodium Fluoride	A source of inorganic fluoride which is used topically to prevent dental caries.	Fluoristat,Ossin,Zymafluor,Fluoride, Sodium,Fluorides, Sodium,Fluoristats,Ossins,Sodium Fluorides,Zymafluors
D015993	Life Tables	Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.	Life Table Analysis,Life Table Methods,Life Table Models,Life Table Estimates,Life Table Method,Analyses, Life Table,Analysis, Life Table,Estimate, Life Table,Estimates, Life Table,Life Table,Life Table Analyses,Life Table Estimate,Life Table Model,Method, Life Table,Methods, Life Table,Model, Life Table,Models, Life Table,Tables, Life