[Cefamandole for perioperative prophylaxis in total hip alloplasty]. 1997

M Jackowiak, and T Buczkowski
Oddziału Urazowo-Ortopedycznego Wojewódzkiego Szpitala Zespolonego w Toruniu.

The aim of this paper was to present the use of Cefamandole as one of the elements in perioperative prophylactics in total hip replacement. One hundred patients operated between 1993 and 1995 were followed-up for mean 13.5 months. There were 33 males and 67 females, mean age was 61.4 years. Cefamandole was administered according to fixed protocol for three days (first dose along with premedication). Mono-antibiotic therapy was sufficient in most cases. No septic complication occurred, no side-effects of Cefamandole were recorded. The patients are still being followed-up. Results achieved resemble these from the literature so conclusion can be made, that Cefamandole is safe and efficient drug for peri-operative prophylactics in total hip replacement.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002435 Cefamandole Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate. Cephamandole,Compound 83405
D002511 Cephalosporins A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid. Antibiotics, Cephalosporin,Cephalosporanic Acid,Cephalosporin,Cephalosporin Antibiotic,Cephalosporanic Acids,Acid, Cephalosporanic,Acids, Cephalosporanic,Antibiotic, Cephalosporin,Cephalosporin Antibiotics
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006622 Hip Prosthesis Replacement for a hip joint. Femoral Head Prosthesis,Femoral Head Prostheses,Hip Prostheses,Prostheses, Femoral Head,Prostheses, Hip,Prosthesis, Femoral Head,Prosthesis, Hip
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D019072 Antibiotic Prophylaxis Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications. Antibiotic Premedication,Premedication, Antibiotic,Antibiotic Premedications,Premedications, Antibiotic,Prophylaxis, Antibiotic

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