Biomaterial Database

Sequelae of secretory otitis media: changes in middle ear biomechanics. 1997

M Gaihede, and T Lildholdt, and J Lunding

Department of Otolaryngology, Aarhus University Hospital, Denmark.

A new method previously introduced investigating the pressure volume relationship of the middle ear system describes dynamic mechanical properties of the system: the variables measured are hysteresis, compliance, and P(ec0) expressing the zero position of the tympanic membrane. The present study investigates the mechanical properties in 69 adolescents treated with ventilation tubes during childhood due to secretory otitis media. The tympanic membranes displayed various degrees of atrophy, sclerosis, and retraction of the pars flaccida. Atrophy was quantitatively related to decreasing hysteresis and increasing compliance, while myringosclerosis showed opposite effects. P(ec0) was significantly lower for the group of former secretory otitis media than for normals (p < 0.001). This reflects a retraction pattern of the tympanic membrane, which may be explained by a low opening pressure of the eustachian tube or previous pressure load of the drum. Signs of retraction were not found by tympanometry. Treatment with ventilation tubes was associated with a dramatic increase of tympanic membrane pathology (66%) compared to untreated ears (12%), as assessed by otomicroscopy (p < 0.001). However, these changes specific to treatment were not found in the corresponding mechanical variables of the middle ear system, as the effects of combined atrophy and myringosclerosis tend to counterbalance.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008876	Middle Ear Ventilation	Ventilation of the middle ear in the treatment of secretory (serous) OTITIS MEDIA, usually by placement of tubes or grommets which pierce the TYMPANIC MEMBRANE.	Grommet Insertion,Tympanostomy Tube Insertion,Ventilation, Middle Ear,Myringostomy,Tympanostomy,Ear Ventilation, Middle,Ear Ventilations, Middle,Grommet Insertions,Insertion, Grommet,Insertion, Tympanostomy Tube,Insertions, Grommet,Insertions, Tympanostomy Tube,Middle Ear Ventilations,Myringostomies,Tube Insertion, Tympanostomy,Tube Insertions, Tympanostomy,Tympanostomies,Tympanostomy Tube Insertions,Ventilations, Middle Ear
D010034	Otitis Media with Effusion	Inflammation of the middle ear with a clear pale yellow-colored transudate.	Middle Ear Effusion,Otitis Media, Secretory,Otitis Media, Serous,Ear Effusion, Middle,Ear Effusions, Middle,Effusion, Middle Ear,Effusions, Middle Ear,Middle Ear Effusions,Secretory Otitis Media,Serous Otitis Media
D011312	Pressure	A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Pressures
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D004432	Ear, Middle	The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.	Tympanic Cavity,Tympanum,Middle Ear,Cavities, Tympanic,Cavity, Tympanic,Ears, Middle,Middle Ears,Tympanic Cavities,Tympanums
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000158	Acoustic Impedance Tests	Objective tests of middle ear function based on the difficulty (impedance) or ease (admittance) of sound flow through the middle ear. These include static impedance and dynamic impedance (i.e., tympanometry and impedance tests in conjunction with intra-aural muscle reflex elicitation). This term is used also for various components of impedance and admittance (e.g., compliance, conductance, reactance, resistance, susceptance).	Audiometry, Impedance,Electroacoustic Impedance Tests,Impedance Tests, Acoustic,Tympanometry,Acoustic Impedance Test,Electroacoustic Impedance Test,Impedance Audiometry,Impedance Test, Acoustic,Impedance Test, Electroacoustic,Impedance Tests, Electroacoustic,Test, Acoustic Impedance,Test, Electroacoustic Impedance,Tests, Acoustic Impedance,Tests, Electroacoustic Impedance