Biomaterial Database

[Laparoscopic cholecystectomy and respiratory function]. 1997

A Tocchi, and G Costa, and L Lepre, and G Liotta, and G Mazzoni

Cattedra di IV Patologia Chirurgica, Università degli Studi La Sapienza, Roma.

A prospective analysis of 58 patients undergoing laparoscopic cholecystectomy was undertaken to assess pulmonary function changes related to the surgical procedure. Pulmonary function tests were performed preoperatively, as well as 24 hrs., and 48 hrs. after operation. Additionally blood gas analysis was assessed 1 hr. and 6 hrs. after the procedure. At 24 hrs. from operation significant decreases in forced vital capacity, forced expiratory volume in 1", and Tidal volume to 72% (p < 0.001), 70% (p < 0.001), and 92% (p < 0.001) of preoperative values respectively were registered. There was a reduction in PaO2 (p < 0.001) and an increase in PaCO2 (p < 0.05) at 24 hrs. An increase in PaCO2 was also observed 1 hr. (p < 0.001) and 6 hrs. (p < 0.05) postoperatively. Blood gas analysis revealed pH value slightly lower than normal at 1 hr. from operation (p < 0.01). The pulmonary function tests returned to preoperative values at 48 hours.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D011184	Postoperative Period	The period following a surgical operation.	Period, Postoperative,Periods, Postoperative,Postoperative Periods
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D005260	Female		Females
D005541	Forced Expiratory Volume	Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.	Forced Vital Capacity, Timed,Timed Vital Capacity,Vital Capacity, Timed,FEVt,Capacities, Timed Vital,Capacity, Timed Vital,Expiratory Volume, Forced,Expiratory Volumes, Forced,Forced Expiratory Volumes,Timed Vital Capacities,Vital Capacities, Timed,Volume, Forced Expiratory,Volumes, Forced Expiratory
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man