History of pediatric hematology-oncology in the Czech Republic. 1997

P Kavan, and V Smelhaus, and J Stary, and K McClain, and J Koutecky
Department of Pediatric Oncology, University Hospital Motol, Prague, Czech Republic. Petr.Kavan@lfMotol.cuni.cz

Specialized treatment for children with hematologic and oncologic diseases in the Czech Republic has a relatively short history. Dr. Josef Koutecky in 1964 was the first to organize the discipline of oncologic treatments and started a department that has since grown to include six other senior members. They treat over 250 new patients a year (approximately 150 malignant tumors) with an incidence similar to that in other European nations. Most are treated on cooperative group protocols with other centers in Europe and North America. Over 30 children also receive bone marrow transplants yearly from this group. Hematologic diseases including leukemia were first treated by D.r. O. Hrodek since the late 1950s in the Second Department of Pediatrics in Prague. Eight other centers in the Czech Republic besides Motol treat children with leukemia. Since 1985 they have followed the Berlin-Frankfurt-Münster (BFM) protocols for patients with acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML). The Motol Hematology Section does about 20 transplants a year. New molecular biology laboratories in both sections aid the diagnosis and follow-up of the patients.

UI MeSH Term Description Entries
D008495 Medical Oncology A subspecialty of internal medicine concerned with the study of neoplasms. Oncology, Medical,Clinical Oncology,Oncology, Clinical
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D010372 Pediatrics A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D006405 Hematology A subspecialty of internal medicine concerned with morphology, physiology, and pathology of the blood and blood-forming tissues.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015994 Incidence The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases in the population at a given time. Attack Rate,Cumulative Incidence,Incidence Proportion,Incidence Rate,Person-time Rate,Secondary Attack Rate,Attack Rate, Secondary,Attack Rates,Cumulative Incidences,Incidence Proportions,Incidence Rates,Incidence, Cumulative,Incidences,Person time Rate,Person-time Rates,Proportion, Incidence,Rate, Attack,Rate, Incidence,Rate, Person-time,Rate, Secondary Attack,Secondary Attack Rates
D018153 Czech Republic Created 1 January 1993 as a result of the division of Czechoslovakia into the Czech Republic and Slovakia.
D019337 Hematologic Neoplasms Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. Blood Cancer,Hematologic Malignancies,Hematopoietic Neoplasms,Hematologic Malignancy,Hematological Malignancies,Hematological Neoplasms,Hematopoietic Malignancies,Malignancies, Hematologic,Malignancy, Hematologic,Neoplasms, Hematologic,Neoplasms, Hematopoietic,Blood Cancers,Cancer, Blood,Hematologic Neoplasm,Hematological Malignancy,Hematological Neoplasm,Hematopoietic Malignancy,Hematopoietic Neoplasm,Malignancy, Hematological,Malignancy, Hematopoietic,Neoplasm, Hematologic,Neoplasm, Hematological,Neoplasm, Hematopoietic

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