Umbilical artery blood gases in healthy term newborn infants. 1997

J W Dudenhausen, and C Luhr, and J S Dimer
Department of Obstetrics, Virchow-Klinikum, Humboldt University, Berlin, Germany. jwdud@ukrv.de

OBJECTIVE To study the distributions of pH and gas values in umbilical arterial (UA) blood of normal newborns following uncomplicated pregnancies and vaginal births. METHODS In 681 consecutive normal term infants who were born during 1990, we examined the UA pH and blood gas values obtained immediately following delivery. Maternal inclusion criteria were defined as an uncomplicated pregnancy and a normal spontaneous vaginal delivery. Umbilical artery blood samples were collected at each birth and were evaluated for pH, carbon dioxide pressure (PaCO2), oxygen pressure (PaO2), bicarbonate, and base excess. All newborns in this study had the following inclusion criteria: singletons, no malformations, growth appropriate for gestational age (AGA), and Apgar scores of 7 or more at 1, 5 and 10 min of life. RESULTS The lowest UA pH was 7.04 and the 10th percentile value was 7.21. The lowest UA PaO2 was 4.6 mmHg and the 10th percentile value was 10.1 mmHg. The highest UA PaCO2 was 75.4 mmHg and the 90th percentile 62 mmHg. The 10th percentile of the base deficit in the extracellular fluid was 5.9 mmol/l. CONCLUSIONS The distributions of the UA pH and gas values of a collective of normal newborns were illustrated.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D010100 Oxygen An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Dioxygen,Oxygen-16,Oxygen 16
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001784 Blood Gas Analysis Measurement of oxygen and carbon dioxide in the blood. Analysis, Blood Gas,Analyses, Blood Gas,Blood Gas Analyses,Gas Analyses, Blood,Gas Analysis, Blood
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D005312 Fetal Blood Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery. Cord Blood,Umbilical Cord Blood,Blood, Cord,Blood, Fetal,Blood, Umbilical Cord,Bloods, Cord,Bloods, Fetal,Bloods, Umbilical Cord,Cord Blood, Umbilical,Cord Bloods,Cord Bloods, Umbilical,Fetal Bloods,Umbilical Cord Bloods
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D000137 Acid-Base Imbalance Disturbances in the ACID-BASE EQUILIBRIUM of the body. Acid Base Imbalance,Acid-Base Imbalances,Imbalance, Acid-Base,Imbalances, Acid-Base
D001639 Bicarbonates Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity. Bicarbonate,Bicarbonate Ions,Hydrogen Carbonates,Bicarbonate Ion,Carbonic Acid Ions,Hydrogen Carbonate,Carbonate, Hydrogen,Carbonates, Hydrogen,Ion, Bicarbonate,Ions, Bicarbonate,Ions, Carbonic Acid

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