The stimulatory effect of negative air ions and hydrogen peroxide on the activity of superoxide dismutase. 1997

E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino.

The activity of erythrocyte cytosolic superoxide dismutase from rat, bovine, man and duck was considerably increased when measured after preparation or incubation in media pretreated with negative air ions (mostly superoxide) from electroeffluvial ion generator. 0.5-1.0 microM H2O2 was found in incubation medium after treatment with air ions. The stimulatory effect of air ions on superoxide dismutase activity was mimicked by addition of 0.5-6 microM H2O2. The primary physicochemical mechanism of beneficial biological action of negative air ions is suggested to be related to the stimulation of superoxide dismutase activity by micromolar concentrations of H2O2.

UI MeSH Term Description Entries
D007477 Ions An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
D002374 Catalase An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA. Catalase A,Catalase T,Manganese Catalase,Mn Catalase
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D004372 Ducks A water bird in the order Anseriformes (subfamily Anatinae (true ducks)) with a broad blunt bill, short legs, webbed feet, and a waddling gait. Duck
D004789 Enzyme Activation Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. Activation, Enzyme,Activations, Enzyme,Enzyme Activations
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006861 Hydrogen Peroxide A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. Hydrogen Peroxide (H2O2),Hydroperoxide,Oxydol,Perhydrol,Superoxol,Peroxide, Hydrogen
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013481 Superoxides Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. Superoxide Radical,Superoxide,Superoxide Anion

Related Publications

E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
March 1987, Biochemistry,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
May 2011, Anti-cancer agents in medicinal chemistry,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
April 1974, The Biochemical journal,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
March 1979, Biochimica et biophysica acta,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
June 1989, The Journal of biological chemistry,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
January 2008, Ukrains'kyi biokhimichnyi zhurnal (1999 ),
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
September 2011, Antioxidants & redox signaling,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
November 1972, FEBS letters,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
November 1986, Biochimica et biophysica acta,
E A Kosenko, and Kaminsky YuG, and I G Stavrovskaya, and T V Sirota, and M N Kondrashova
January 1997, Andrologia,
Copied contents to your clipboard!