-transparent.png){kind=logo}
TM rats have a light brown hooded coat pattern resembling that of Fawn hooded (FH) rats which are a model of platelet storage pool deficiency (SPD). We examined whether the TM strain has the same platelet SPD as the FH strain. TM rats had a prolonged bleeding time and a low blood serotonin level, although their blood coagulation time and platelet counts were normal. The light coat color of the TM strain was judged to be associated with the red-eyed dilution gene as in the FH strain, but not pink eye dilution as in the RCS rat strain. Platelet SPD seen in TM rats may be a pleiotropic effect of the red-eyed dilution gene proposed in FH rats. Despite these similarities, the genetic background of the TM strain was obviously different from that of the FH strain. The TM strain, developed independently of the FH strain, will therefore be used as a model of platelet SPD.
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
October 1998,
Laboratory animal science,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
August 1991,
Genetical research,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
July 1988,
British journal of haematology,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
January 1995,
The British journal of clinical practice,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
April 1986,
Blood,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
November 2007,
Platelets,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
April 2003,
The Australian & New Zealand journal of obstetrics & gynaecology,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
July 1991,
Polskie Archiwum Medycyny Wewnetrznej,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
November 1992,
Leukemia & lymphoma,
S Hamada, and
T Nishikawa, and
N Yokoi, and
T Serikawa
January 1982,
Artery,
