Influence of phenobarbital on the disposition of clonazepam and antipyrine in the dog. 1977

I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D008297 Male Males
D010634 Phenobarbital A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. Phenemal,Phenobarbitone,Phenylbarbital,Gardenal,Hysteps,Luminal,Phenobarbital Sodium,Phenobarbital, Monosodium Salt,Phenylethylbarbituric Acid,Acid, Phenylethylbarbituric,Monosodium Salt Phenobarbital,Sodium, Phenobarbital
D002998 Clonazepam An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses. 2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-,Klonopin,Antelepsin,Rivotril,Ro 5-4023,Ro 54023
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004347 Drug Interactions The action of a drug that may affect the activity, metabolism, or toxicity of another drug. Drug Interaction,Interaction, Drug,Interactions, Drug
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000983 Antipyrine An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29) Phenazone,Anodynin,Pyramidone
D001570 Benzodiazepinones

Related Publications

I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
September 1980, Clinical pharmacology and therapeutics,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
January 1984, Pharmacology,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
March 1985, Journal of pharmaceutical sciences,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
January 1988, European journal of drug metabolism and pharmacokinetics,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
March 1973, Arzneimittel-Forschung,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
January 1997, Research in veterinary science,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
August 1983, Xenobiotica; the fate of foreign compounds in biological systems,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
February 1981, The American journal of psychiatry,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
November 1979, Xenobiotica; the fate of foreign compounds in biological systems,
I Bekersky, and A C Maggio, and V Mattaliano, and H G Boxenbaum, and D E Maynard, and P D Cohn, and S A Kaplan
March 1990, Biopharmaceutics & drug disposition,
Copied contents to your clipboard!