BIOMAT Database Logo BIOMAT Database Logo

Cyclosporin A in the treatment of adult onset Still's disease. 1997

A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Rheumatology Unit, University of Milan, G. Pini Orthopaedic Institute, Italy.

OBJECTIVE To determine whether cyclosporin A (CyA) is a useful option in the treatment of adult onset Still's disease (ASD). METHODS Low dose CyA was given to 6 patients with chronic or relapsing ASD who had not been prescribed any other second line agents during the previous 6 mo. RESULTS The disease completely remitted in 4 patients and improved markedly in the remaining 2. The corticosteroid requirement was substantially reduced in all cases. Tolerability was rated good or very good by all patients but one, who reported good tolerance to CyA only in a new formulation. CONCLUSIONS CyA may be included among the second line agents used in the treatment of refractory ASD.

UI MeSH Term Description Entries
D008297 Male Males
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000284 Administration, Oral The giving of drugs, chemicals, or other substances by mouth. Drug Administration, Oral,Administration, Oral Drug,Oral Administration,Oral Drug Administration,Administrations, Oral,Administrations, Oral Drug,Drug Administrations, Oral,Oral Administrations,Oral Drug Administrations
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D016572 Cyclosporine A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed). Cyclosporin A,Ciclosporin,CsA-Neoral,CyA-NOF,Cyclosporin,Cyclosporine A,Neoral,OL 27-400,Sandimmun,Sandimmun Neoral,Sandimmune,CsA Neoral,CsANeoral,CyA NOF,OL 27 400,OL 27400
D016706 Still's Disease, Adult-Onset Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent. Adult-Onset Still Disease,Adult-Onset Still's Disease,Still Disease, Adult-Onset,Adult Onset Still Disease,Adult Onset Still's Disease,Adult-Onset Stills Disease,Still Disease, Adult Onset,Still's Disease, Adult Onset,Stills Disease, Adult-Onset
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D018501 Antirheumatic Agents Drugs that are used to treat RHEUMATOID ARTHRITIS. Anti-Rheumatic Agent,Anti-Rheumatic Drug,Antirheumatic Agent,Antirheumatic Disease-Modifying Second-Line Drug,Antirheumatic Drug,DMARD,Disease-Modifying Antirheumatic Drug,Disease-Modifying Antirheumatic Drugs,Anti-Rheumatic Agents,Anti-Rheumatic Agents, Non-Steroidal,Anti-Rheumatic Drugs,Antirheumatic Disease-Modifying Second-Line Drugs,Antirheumatic Drugs,Antirheumatic Drugs, Disease-Modifying,Disease-Modifying, Antirheumatic Second-Line Drugs,Agent, Anti-Rheumatic,Agent, Antirheumatic,Anti Rheumatic Agent,Anti Rheumatic Agents,Anti Rheumatic Agents, Non Steroidal,Anti Rheumatic Drug,Anti Rheumatic Drugs,Antirheumatic Disease Modifying Second Line Drug,Antirheumatic Disease Modifying Second Line Drugs,Antirheumatic Drug, Disease-Modifying,Antirheumatic Drugs, Disease Modifying,Disease Modifying Antirheumatic Drug,Disease Modifying Antirheumatic Drugs,Disease Modifying, Antirheumatic Second Line Drugs,Drug, Anti-Rheumatic,Drug, Antirheumatic,Drug, Disease-Modifying Antirheumatic,Non-Steroidal Anti-Rheumatic Agents

Related Publications

A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Cyclosporin A treatment for Japanese patients with severe adult-onset Still's disease.
January 2009, Modern rheumatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Cyclosporin A in the treatment of adult Still's disease.
July 1995, The Journal of rheumatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Treatment of adult-onset Still's disease: a review.
January 2015, Therapeutics and clinical risk management,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Biological treatment in adult-onset Still's disease.
August 2012, Best practice & research. Clinical rheumatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Adult-onset Still's disease: Advances in the treatment.
April 2016, Best practice & research. Clinical rheumatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
[Still's disease, adult-onset Still's disease (AOSD)].
September 2006, Praxis,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Adult-onset Still's disease.
July 1995, International journal of dermatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
[Adult-onset Still's disease].
March 2008, Revue medicale suisse,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Adult-onset Still's disease.
October 2004, Best practice & research. Clinical rheumatology,
A Marchesoni, and G P Ceravolo, and N Battafarano, and A Rossetti, and S Tosi, and F Fantini
Adult-onset Still's disease.
May 1976, American family physician,
Copied contents to your clipboard!